Liquid Chromatography-Mass Spectrometry (LC-MS/MS)
Liquid Chromatography-Mass Spectrometry (LC-MS/MS)
The system consists of the LC3600 ultra-high-performance liquid chromatograph and the TQ9200 triple quadrupole mass spectrometer. It incorporates core technologies such as an ultra-high-pressure direct-drive pump, ultra-high-pressure needle-in-flowpath lossless injection, an actively preheated column oven, a highly stable EI source, a high-durability vacuum interface, high-efficiency ion transfer lenses, and a tandem quadrupole high-stability drive system. These innovations collectively deliver stable, sensitive, and durable instrument performance.
Introduction of LC-MS/MS
The system consists of the LC3600 ultra-high-performance liquid chromatograph and the TQ9200 triple quadrupole mass spectrometer. It incorporates core technologies such as an ultra-high-pressure direct-drive pump, ultra-high-pressure needle-in-flowpath lossless injection, an actively preheated column oven, a highly stable EI source, a high-durability vacuum interface, high-efficiency ion transfer lenses, and a tandem quadrupole high-stability drive system. These innovations collectively deliver stable, sensitive, and durable instrument performance.
Technical Parameters of TQ9200
| Working conditions | |
| Working power supply | 220V±22V, 50Hz±0.5Hz |
| Ambient temperature | 15-30°C |
| Relative humidity | not more than 80% |
| UHPLC | |
| Pump drive mode | linear motor pump |
| Gradient mode | binary (4-waysolvent) |
| Flow rate setting range | 0.001-2.000mL/min |
| Flow rate setting increment | 0.001mL/min |
| Maximumoperating pressure | 150MPa |
| Degassing | 5-channel online degassing |
| Autosampler | |
| Maximumwithstand pressure | 150MPa |
| Sampling volume range | 0.1-20.0μL (50μL optional) |
| Linearity | R≥0.9999 |
| Cross-contamination | <0.004 % |
| Number of samples | 108 (2*54,2 ml), supports 96 shallow well plate, 96 deep well plate, 384 well plate |
| Temperature setting range | 4.0~40.0 ℃ (optional refrigeration) |
| Temperature stability | ±2 ℃ |
| Feed rate | 12s |
| Column temperaturechamber | |
| Temperature setting range | 20.0-90.0 ℃ |
| Temperature stability | ±0.02 ℃/h |
| Temperature setting value error | ± 0.1 ℃ |
| Triple quadrupole mass spectrometer | |
| Mass analysis range | 5-1250 |
| Scanning speed | 12000 Da/s |
| Mass resolution | 0.6-0.8 Da (609 mass peaks) |
| Linearity range | ≥1E4 |
| Mass accuracy | 0.1 Da |
| Massstability | 0.1 Da/24h |
| Limit of detection (rifampicin) | 0.1pg |
| Sensitivity | S:N >20w:1 on a 1pg Risperdal column |
| System indicators | |
| Qualitative reproducibility | RSD≤5% |
| Quantitative reproducibility | RSD≤5% |